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Rituximab therapy for refractory interstitial lung disease related to antisynthetase syndrome
27 January 2012
I. Marie, S. Dominique, A. Janvresse, H. Levesque, J-F. Menard
Summary: Objective: To report our experience using rituximab as therapy for refractory antisynthetase syndrome (ASS)-associated interstitial lung disease. Methods: We retrospectively evaluated the med...
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Inhaler mishandling is very common in patients with chronic airflow obstruction and long-term home nebuliser use
25 January 2012
Andrea S. Melani, PierAldo Canessa, Isotta Coloretti, Giuseppe DeAngelis, Renato DeTullio, Mario DelDonno, Raffaela Giacobbe, Ines Scarlato, Antonella Serafini, Natalino Barbato, Adriano Vaghi, Piersante Sestini
Summary: Inhalers and nebulisers are devices used for delivering aerosolised drugs in subjects with Chronic Airflow Obstruction (CAO). This multicentre, cross-sectional observational study was perform...
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Impact of add-on pranlukast in stable asthma; the additive effect on peripheral airway inflammation
24 January 2012
Hideki Yasui, Tomoyuki Fujisawa, Naoki Inui, Masato Kato, Dai Hashimoto, Noriyuki Enomoto, Yutaro Nakamura, Toshihiro Shirai, Takafumi Suda, Hirotoshi Nakamura, Kingo Chida
Summary: Backgound: The importance of airway inflammation has been highlighted in the pathophysiology of asthma. Even in controlled asthmatics treated with inhaled corticosteroid (ICS), residual airwa...
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Raised erythrocyte creatine in patients with pulmonary arterial hypertension – Evidence for subclinical hemolysis
16 January 2012
Benjamin D. Fox, Toshika Okumiya, Liat Attas-Fox, Michael Kassirer, Yael Raviv, Mordechai R. Kramer
Summary: Background: Pulmonary arterial hypertension (PAH) has been associated with hemolytic conditions such as sickle cell disease but the possible role of hemolysis in the pathogenesis or pathophys...
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Lung capillary blood volume and membrane diffusion in idiopathic interstitial pneumonia
06 January 2012
Lidwine Wémeau-Stervinou, Thierry Perez, Colm Murphy, Anne-Sophie Polge, Benoît Wallaert
Summary: Rationale: Diffusing capacity of the lung for carbon monoxide (DLCO) is a good marker of disease severity in patients with idiopathic interstitial pneumonia (IIP). The combined diffusing capa...
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