A comparison of three disease-specific and two generic health-status measures to evaluate the outcome of pulmonary rehabilitation in COPD

Abstract 

The use of health status as an outcome measure is becoming more widespread in pulmonary rehabilitation. There are a number of health status measures but the choice remains uncertain. Three disease specific measures and two generic measures of health status were employed to observe their relative sensitivity to a 7-week course of pulmonary rehabilitation.

Patients with stable chronic obstructive pulmonary disease (COPD) were recruited into a rehabilitation programme. They completed a shuttle-walking test and three disease-specific questionnaires: the Chronic Respiratory Questionnaire (CRQ), the St. George's Hospital Respiratory Questionnaire (SGRQ) and the Breathing Problems Questionnaire (BPQ). Patients also completed two generic questionnaires: a global quality-of-life scale and an activity checklist. Ninety-seven patients [58 male mean () age 67 (8·7) years] completed the course over a 12-month period. The mean pre-rehabilitation () FEV₁was 1·06 (0·59)l. The shuttle-walking test and the treadmill-endurance test increased significantly after rehabilitation (P<0·001). All three disease-specific questionnaires improved significantly (the CRQ and SGRQ improved beyond minimum clinically important difference). The global score improved significantly whilst the ‘things people do’ decreased.

All three disease-specific measures were responsive to pulmonary rehabilitation. However the operator-led CRQ appears to be the most sensitive short-term outcome measure.

Keywords: health status, pulmonary rehabilation, COPD.

No full text is available. To read the body of this article, please view the PDF online.

• f1 Correspondence should be addressed to: S. J. Singh, University Hospitals of Leicester NHS Trust, Department of Respiratory Medicine, Glenfield Hospital, Groby Rd, Leicester, LE3 9QP, U.K. Fax: +44 (0) 116 2567738; E-mail: sally.singh@glenfield-tr.trent.nhs.uk