Respiratory Medicine
Volume 101, Issue 10 , Pages 2051-2055 , October 2007

Effect of continuous positive airway pressure combined to nebulization on lung deposition measured by urinary excretion of amikacin

  • Gregory Reychler

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    • Department of Pediatry, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    • Corresponding Author InformationCorresponding author. Department of Physical Medicine and Rehabilitation Cliniques, Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium. Tel.: +3227641939; fax: +3227648906.
  • ,
  • Teresinha Leal

      Affiliations

    • Department of Clinical Chemistry, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
  • ,
  • Jean Roeseler

      Affiliations

    • Department of Physical Medicine and Rehabilitation, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
    • Department of Emergency and Intensive Care, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
  • ,
  • Frédéric Thys

      Affiliations

    • Department of Emergency and Intensive Care, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
  • ,
  • Nicolas Delvau

      Affiliations

    • Department of Emergency and Intensive Care, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
  • ,
  • Giuseppe Liistro

      Affiliations

    • Pneumology Unit, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium

Received 16 December 2006 ,Accepted 3 June 2007.

Reference 

  1. Dolovich MB, Ahrens RC, Hess DR, Anderson P, Dhand R, Rau JL, et al. Device selection and outcomes of aerosol therapy: evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest. 2005;127(1):335–371
  2. Finegold SM. Kanamycin. AMA Arch Intern Med. 1959;104(1):15–28
  3. Clarke JT, Libke RD, Regamey C, Kirby WM. Comparative pharmacokinetics of amikacin and kanamycin. Clin Pharmacol Ther. 1974;15(6):610–616
  4. Dequin PF, Faurisson F, Lemarie E, Delatour F, Marchand S, Valat C, et al. Urinary excretion reflects lung deposition of aminoglycoside aerosols in cystic fibrosis. Eur Respir J. 2001;18(2):316–322
  5. Ilowite JS, Gorvoy JD, Smaldone GC. Quantitative deposition of aerosolized gentamicin in cystic fibrosis. Am Rev Respir Dis. 1987;136(6):1445–1449
  6. Palmer LB, Smaldone GC, Simon SR, O’Riordan TG, Cuccia A. Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Crit Care Med. 1998;26(1):31–39
  7. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–338
  8. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report working party standardization of lung function tests. European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:5–40.
  9. Coates AL, Allen PD, MacNeish CF, Ho SL, Lands LC. Effect of size and disease on estimated deposition of drugs administered using jet nebulization in children with cystic fibrosis. Chest. 2001;119(4):1123–1130
  10. Kesten S, Rebuck AS. Ventilatory effects of nasal continuous positive airway pressure. Eur Respir J. 1990;3(5):498–501
  11. Hakkinen AM, Uusi-Heikkila H, Jarvinen M, Saali K, Karhumaki L. The effect of breathing frequency on deposition of drug aerosol using an inhalation-synchronized dosimeter in healthy adults. Clin Physiol. 1999;19(3):269–274
  12. Neale MG, Brown K, Hodder RW, Auty RM. The pharmacokinetics of sodium cromoglycate in man after intravenous and inhalation administration. Br J Clin Pharmacol. 1986;22(4):373–382
  13. O’Callaghan C, Barry PW. The science of nebulised drug delivery. Thorax. 1997;52(Suppl 2):S31–S44
  14. Parkes SN, Bersten AD. Aerosol kinetics and bronchodilator efficacy during continuous positive airway pressure delivered by face mask. Thorax. 1997;52(2):171–175
  15. Dolovich MB, Killian D, Wolff RK, Obminski G, Newhouse MT. Pulmonary aerosol deposition in chronic bronchitis: intermittent positive pressure breathing versus quiet breathing. Am Rev Respir Dis. 1977;115(3):397–402
  16. Reychler G, Keyeux A, Cremers C, Veriter C, Rodenstein DO, Liistro G. Comparison of lung deposition in two types of nebulization: intrapulmonary percussive ventilation versus jet nebulization. Chest. 2004;125(2):502–508
  17. Reychler G, Wallemacq P, Rodenstein DO, Cumps J, Leal T, Liistro G. Comparison of lung deposition of amikacin by intrapulmonary percussive ventilation and jet nebulization by urinary monitoring. J Aerosol Med. 2006;19(2):199–207
  18. Franca EE, Dornelas de Andrade AF, Cabral G, Almeida FP, Silva KC, Galindo FV, et al. Nebulization associated with bi-level noninvasive ventilation: analysis of pulmonary radioaerosol deposition. Respir Med. 2006;100(4):721–728
  19. Laube BL, Geller DE, Lin TC, Dalby RN, Diener-West M, Zeitlin PL. Positive expiratory pressure changes aerosol distribution in patients with cystic fibrosis. Respir Care. 2005;50(11):1438–1444
  20. Melchor R, Biddiscombe MF, Mak VH, Short MD, Spiro SG. Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airflow obstruction. Thorax. 1993;48(5):506–511
  21. Matthay MA. Function of the alveolar epithelial barrier under pathologic conditions. Chest. 1994;105(3 Suppl):67S–74S
  22. Cooney GF, Lum BL, Tomaselli M, Fiel SB. Absolute bioavailability and absorption characteristics of aerosolized tobramycin in adults with cystic fibrosis. J Clin Pharmacol. 1994;34(3):255–259
  23. Oeltgen PR, Shank WA, Blouin RA, Clark T. Clinical evaluation of the Abbott TDx fluorescence polarization immunoassay analyzer. Ther Drug Monit. 1984;6(3):360–367

PII: S0954-6111(07)00257-0

doi: 10.1016/j.rmed.2007.06.003

Respiratory Medicine
Volume 101, Issue 10 , Pages 2051-2055 , October 2007