Respiratory Medicine
Volume 103, Issue 8 , Pages 1167-1173, August 2009

Comparative in vitro evaluation of four corticosteroid metered dose inhalers: Consistency of delivered dose and particle size distribution

  • Tjalling W. de Vries

      Affiliations

    • Department of Paediatrics, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 58 2863385; fax: +31 58 2863390.
  • ,
  • Bart L. Rottier

      Affiliations

    • Beatrix Children's Hospital, Division of Paediatric Pulmonology and Allergology, University Hospital Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands
  • ,
  • Doetie Gjaltema

      Affiliations

    • Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Ant. Deusinglaan 1, 9713 AV Groningen, The Netherlands
  • ,
  • Paul Hagedoorn

      Affiliations

    • Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Ant. Deusinglaan 1, 9713 AV Groningen, The Netherlands
  • ,
  • Henderik W. Frijlink

      Affiliations

    • Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Ant. Deusinglaan 1, 9713 AV Groningen, The Netherlands
  • ,
  • Anne H. de Boer

      Affiliations

    • Department of Pharmaceutical Technology and Biopharmacy, University of Groningen, Ant. Deusinglaan 1, 9713 AV Groningen, The Netherlands

Received 27 September 2008; accepted 14 February 2009. published online 09 March 2009.

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PII: S0954-6111(09)00061-4

doi:10.1016/j.rmed.2009.02.010

Respiratory Medicine
Volume 103, Issue 8 , Pages 1167-1173, August 2009