Respiratory Medicine
Volume 104, Issue 7 , Pages 1035-1041 , July 2010

Prevalence and impact of coronary artery disease in idiopathic pulmonary fibrosis

  • Steven D. Nathan

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 (703) 776 3610; fax: +1 (703) 776 3515.
  • ,
  • Ashwin Basavaraj

      Affiliations

    • Georgetown University Medical Center, Washington, DC, USA
  • ,
  • Cristina Reichner

      Affiliations

    • Georgetown University Medical Center, Washington, DC, USA
  • ,
  • Oksana A. Shlobin

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA
  • ,
  • Shahzad Ahmad

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA
  • ,
  • Joseph Kiernan

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA
  • ,
  • Nelson Burton

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA
  • ,
  • Scott D. Barnett

      Affiliations

    • Inova Transplant Center, Inova Fairfax Hospital, 3300 Gallows Road, Falls Church, VA 22042, USA

Received 27 October 2009 ,Accepted 9 February 2010.

References 

  1. Raghu G, Weycker D, Edelsberg J, Bradford WZ, Oster G. Incidence and prevalence of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2006;174:810–816
  2. Olson AL, Swigris JJ, Lezotte DC, Norris KM, Wilson CG, Brown KK. Mortality from pulmonary fibrosis increased in the United States from 1992 to 2003. Am J Respir Crit Care Med. 2007;176:277–284
  3. Gribbin J, Hubbard RB, Le Jeune I, Smith CJ, West J, Tata LJ. The incidence and mortality of idiopathic pulmonary fibrosis and sarcoidosis in the UK. Thorax. 2006;61:980–985
  4. Coultas DB, Zumwalt RE, Black WC, Sobonya RE. The epidemiology of interstitial lung diseases. Am J Respir Crit Care Med. 1994;150:967–972
  5. Hunninghake GW, Schwarz MI. Does current knowledge explain the pathogenesis of idiopathic pulmonary fibrosis? A perspective. Proc Am Thorac Soc. 2007;4:449–452
  6. Kizer JR, Zisman DA, Blumenthal NP, et al. Association between pulmonary fibrosis and coronary artery disease. Arch Intern Med. 2004;164:551–556
  7. Hubbard RB, Smith C, Le Jeune I, Gribbin J, Fogarty AW. The association between idiopathic pulmonary fibrosis and vascular disease. Am J Respir Crit Care Med. 2008;178:1257–1261
  8. Ponnuswamy A, Manikandan R, Sabetpour A, Keeping IM, Finnerty JP. Association between ischaemic heart disease and interstitial lung disease: a case–control study. Resp Med. 2009;103:503–507
  9. Izbicki G, Ben-Dor I, Shitrit D, et al. The prevalence of coronary artery disease in end-stage pulmonary disease: is pulmonary fibrosis a risk factor?. Resp Med. 2009;103(9):1346–1349
  10. American Thoracic Society/European Respiratory Society International multidisciplinary consensus classifications of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med. 2002;165:277–304
  11. King TE, Tooze JA, Schwarz MI, Brown KR, Cherniack RM. Predicting survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2001;164:1171–1181
  12. Reichner CA, Nathan SD, Barnett SD, Keller A, Ahmad S, Burton N. Prevalence and impact on outcomes of coronary artery disease in patients with IPF. Am J Respir Crit Care Med. 2004;169:A108
  13. Idiopathic pulmonary fibrosis: diagnosis and treatment. International consensus statement. American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med. 2000;161:646–664
  14. Panos RJ, Mortenson RL, Niccoli SA, King TE. Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment. Am J Med. 1990;88:396–404
  15. Tobin RW, Pope CE, Pellegrini CA, Emond MJ, Sillery J, Raghu G. Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 1998;158:1804–1808
  16. Mermigkis C, Chapman J, Golish J, et al. Sleep-related breathing disorders in patients with idiopathic pulmonary fibrosis. Lung. 2007;185:173–178
  17. Caplan-Shaw CE, Arcasoy SM, Shane E, et al. Osteoporosis in diffuse parenchymal lung disease. Chest. 2006;129:140–146
  18. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340:115–126
  19. Hayashi M, Fujimoto K, Urushibata K, Uchikawa S, Imamura H, Kubo K. Nocturnal oxygen desaturation correlates with the severity of coronary atherosclerosis in coronary artery disease. Chest. 2003;124:936–941
  20. Heart disease and stroke statistics-2004 update. Coronary heart disease, acute coronary syndrome and angina pectoris. Am Heart Assoc. 2004;6:9–12
  21. Iwamoto H, Yokoyama A, Kitahara Y, et al. Airflow limitation in smokers is associated with subclinical atherosclerosis. Am J Respir Crit Care Med. 2009;179:35–40
  22. Maclay JD, McAllister DA, Macnee W. Cardiovascular risk in chronic obstructive pulmonary disease. Respirology. 2007;12:634–641
  23. Leibowitz DW, Caputo AL, Shapiro GC, et al. Coronary angiography in smokers undergoing evaluation for lung transplantation: is routine use justified?. J Heart Lung Transplant. 1994;13:701–703
  24. Henzlova MJ, Padilla ML, Freilich A, et al. Dobutamine thallium 201 perfusion imaging in candidates for lung transplantation. J Heart Lung Transplant. 1995;14:251–256
  25. Thaik CM, Semigran MJ, Ginns L, Wain JC. Evaluation of ischemic heart disease in potential lung transplant recipients. J Heart Lung Transplant. 1995;14:257–266
  26. Mannino DM, Thorn D, Swensen A, Holguin F. Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD. Eur Respir J. 2008;32:962–969

 This study was unfunded. None of the authors have any financial conflicts of interest relevant to the subject of this manuscript.

PII: S0954-6111(10)00059-4

doi: 10.1016/j.rmed.2010.02.008

Respiratory Medicine
Volume 104, Issue 7 , Pages 1035-1041 , July 2010