Respiratory Medicine
Volume 104, Issue 8 , Pages 1197-1203 , August 2010

Relationship of body composition and C-reactive protein with pulmonary function

  • Dong-Hyuk Jung

      Affiliations

    • Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea
  • ,
  • Jae-Yong Shim

      Affiliations

    • Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea
  • ,
  • Hong-Yup Ahn

      Affiliations

    • Department of Stastistics, Dongguk University, Seoul, Korea
  • ,
  • Hye-Ree Lee

      Affiliations

    • Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea
  • ,
  • Jung-Hyun Lee

      Affiliations

    • Department of Health Promotion Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • ,
  • Yong-Jae Lee

      Affiliations

    • Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea
    • Corresponding Author InformationCorresponding author at: Department of Family Medicine, Yonsei University College of Medicine, 23 Yongmun-ro, Yongin-city, Gyeonggi-do, Korea, Tel.: +82 31 331 8710; fax: +82 31 331 5551.

Received 16 September 2009 ,Accepted 17 February 2010.

References 

  1. Hjalmarsen A, Aasebo U, Birkeland K, et al. Impaired glucose tolerance in patients with chronic hypoxic pulmonary disease. Diabetes Metab. 1996;22:37–42
  2. Larsen JJ, Hansen JM, Olsen NV, et al. The effect of altitude hypoxia on glucose homeostasis in men. J Physiol. 1997;504(Pt 1):241–249
  3. Ford ES, Mannino DM. Prospective association between lung function and the incidence of diabetes: findings from the national health and nutrition examination survey epidemiologic follow-up study. Diabetes Care. 2004;27:2966–2970
  4. Lazarus R, Sparrow D, Weiss ST. Baseline ventilatory function predicts the development of higher levels of fasting insulin and fasting insulin resistance index: the normative aging study. Eur Respir J. 1998;12:641–645
  5. Ochs-Balcom HM, Grant BJ, Muti P, et al. Pulmonary function and abdominal adiposity in the general population. Chest. 2006;129:853–862
  6. Aronson D, Bartha P, Zinder O, et al. Obesity is the major determinant of elevated c-reactive protein in subjects with the metabolic syndrome. Int J Obes Relat Metab Disord. 2004;28:674–679
  7. Steele RM, Finucane FM, Griffin SJ, et al. Obesity is associated with altered lung function independently of physical activity and fitness. Obes (Silver Spring). 2009;17:578–584
  8. Lazarus R, Sparrow D, Weiss ST. Effects of obesity and fat distribution on ventilatory function: the normative aging study. Chest. 1997;111:891–898
  9. Ceylan E, Comlekci A, Akkoclu A, et al. The effects of body fat distribution on pulmonary function tests in the overweight and obese. South Med J. 2009;102:30–35
  10. Collins LC, Hoberty PD, Walker JF, et al. The effect of body fat distribution on pulmonary function tests. Chest. 1995;107:1298–1302
  11. Sutherland TJ, Goulding A, Grant AM, et al. The effect of adiposity measured by dual-energy x-ray absorptiometry on lung function. Eur Respir J. 2008;32:85–91
  12. Costa D, Barbalho MC, Miguel GP, et al. The impact of obesity on pulmonary function in adult women. Clin (Sao Paulo). 2008;63:719–724
  13. Hancock A, Armstrong L, Gama R, et al. Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. Am J Respir Cell Mol Biol. 1998;18:60–65
  14. Maestrelli P, Saetta M, Mapp CE, et al. Remodeling in response to infection and injury. Airway inflammation and hypersecretion of mucus in smoking subjects with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2001;164:S76–S80
  15. Pauwels RA, Buist AS, Calverley PM, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Nhlbi/who global initiative for chronic obstructive lung disease (gold) workshop summary. Am J Respir Crit Care Med. 2001;163:1256–1276
  16. Aronson D, Roterman I, Yigla M, et al. Inverse association between pulmonary function and c-reactive protein in apparently healthy subjects. Am J Respir Crit Care Med. 2006;174:626–632
  17. Riediker M, Cascio WE, Griggs TR, et al. Particulate matter exposure in cars is associated with cardiovascular effects in healthy young men. Am J Respir Crit Care Med. 2004;169:934–940
  18. Mukae H, Vincent R, Quinlan K, et al. The effect of repeated exposure to particulate air pollution (pm10) on the bone marrow. Am J Respir Crit Care Med. 2001;163:201–209
  19. Lee HM, Le TV, Lopez VA, et al. Association of c-reactive protein with reduced forced vital capacity in a nonsmoking u.S. Population with metabolic syndrome and diabetes. Diabetes Care. 2008;31:2000–2002
  20. American thoracic society . Standardization of spirometry, 1994 update. Am J Respir Crit Care Med. 1995;152:1107–1136
  21. Morris JF. Spirometry in the evaluation of pulmonary function. West J Med. 1976;125:110–118
  22. Lin WY, Yao CA, Wang HC, et al. Impaired lung function is associated with obesity and metabolic syndrome in adults. Obes (Silver Spring). 2006;14:1654–1661
  23. Wannamethee SG, Shaper AG, Whincup PH. Body fat distribution, body composition, and respiratory function in elderly men. Am J Clin Nutr. 2005;82:996–1003
  24. Joshi AR, Singh R. Correlation of pulmonary function tests with body fat percentage in young individuals. Indian J Physiol Pharmacol. 2008;52:383–388
  25. Santana H, Zoico E, Turcato E, et al. Relation between body composition, fat distribution, and lung function in elderly men. Am J Clin Nutr. 2001;73:827–831
  26. Amara CE, Koval JJ, Paterson DH, et al. Lung function in older humans: the contribution of body composition, physical activity and smoking. Ann Hum Biol. 2001;28:522–536
  27. Murugan AT, Sharma G. Obesity and respiratory diseases. Chron Respir Dis. 2008;5:233–242
  28. Jones RL, Nzekwu MM. The effects of body mass index on lung volumes. Chest. 2006;130:827–833
  29. Poulain M, Doucet M, Major GC, et al. The effect of obesity on chronic respiratory diseases: pathophysiology and therapeutic strategies. CMAJ. 2006;174:1293–1299
  30. Mattsson C, Olsson T. Estrogens and glucocorticoid hormones in adipose tissue metabolism. Curr Med Chem. 2007;14:2918–2924
  31. Koziel S, Ulijaszek SJ, Szklarska A, et al. The effects of fatness and fat distribution on respiratory functions. Ann Hum Biol. 2007;34:123–131
  32. Canoy D, Luben R, Welch A, et al. Abdominal obesity and respiratory function in men and women in the epic-norfolk study, united kingdom. Am J Epidemiol. 2004;159:1140–1149
  33. Harik-Khan RI, Wise RA, Fleg JL. The effect of gender on the relationship between body fat distribution and lung function. J Clin Epidemiol. 2001;54:399–406
  34. Cartier A, Cote M, Lemieux I, et al. Sex differences in inflammatory markers: what is the contribution of visceral adiposity?. Am J Clin Nutr. 2009;89:1307–1314
  35. Lemieux S, Prud'homme D, Bouchard C, et al. Sex differences in the relation of visceral adipose tissue accumulation to total body fatness. Am J Clin Nutr. 1993;58:463–467
  36. Weisberg SP, McCann D, Desai M, et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796–1808
  37. Ikonomidis I, Stamatelopoulos K, Lekakis J, et al. Inflammatory and non-invasive vascular markers: the multimarker approach for risk stratification in coronary artery disease. Atherosclerosis. 2008;199:3–11
  38. Sabatine MS, Morrow DA, de Lemos JA, et al. Multimarker approach to risk stratification in non-st elevation acute coronary syndromes: simultaneous assessment of troponin i, c-reactive protein, and b-type natriuretic peptide. Circulation. 2002;105:1760–1763
  39. Ford ES, Giles WH, Mokdad AH, et al. Distribution and correlates of c-reactive protein concentrations among adult us women. Clin Chem. 2004;50:574–581
  40. Ford ES, Giles WH, Myers GL, et al. Population distribution of high-sensitivity c-reactive protein among us men: findings from national health and nutrition examination survey 1999-2000. Clin Chem. 2003;49:686–690
  41. Kelley-Hedgepeth A, Lloyd-Jones DM, Colvin A, et al. Ethnic differences in c-reactive protein concentrations. Clin Chem. 2008;54:1027–1037
  42. Wen J, Liang Y, Wang F, et al. Association of c-reactive protein and metabolic syndrome in a rural chinese population. Clin Biochem. 2009;42:976–983
  43. Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American heart association. Circulation. 2003;107:499–511

PII: S0954-6111(10)00084-3

doi: 10.1016/j.rmed.2010.02.014

Respiratory Medicine
Volume 104, Issue 8 , Pages 1197-1203 , August 2010