« Previous
Next »
Respiratory Medicine
Volume 104, Issue 7
, Pages 995-1004
, July 2010
Combining tiotropium and salmeterol in COPD: Effects on airflow obstruction and symptoms
References
- From the Global Strategy for the Diagnosis, Management and prevention of COPD, global initiative for chronic obstructive lung disease (GOLD) update 2008. Available from: www.goldcopd.org (accessed: November 28, 2008).
- ATS/ERS Task Force . Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004;23:932–946
- . Maintenance pharmacotherapy of chronic obstructive pulmonary disease: an evidence-based approach. Expert Opin Pharmacother. 2005;6:13–25
- . Recent developments in inhaled therapy in stable chronic obstructive pulmonary disease. BMJ. 2005;330:640–644
- . Tiotropium as essential maintenance therapy in COPD. Eur Respir J. 2006;15:51–57
- . Long-acting bronchodilator therapy for the treatment of chronic obstructive pulmonary disease. Ann Pharmacother. 2008;42:1832–1842
- . Formoterol for chronic obstructive pulmonary disease: a review of the literature. Pharmacotherapy. 2002;22:1129–1139
- . Inhaled salmeterol: a review of its efficacy in chronic obstructive pulmonary disease. Drugs Aging. 2001;18:441–472
- . The functional impact of adding salmeterol and tiotropium in patients with stable COPD. Respir Med. 2004;98:1214–1221
- Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD. Eur Respir J. 2005;26:214–222
- Effects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. Chest. 2006;129:509–517
- Tiotropium in combination with placebo, salmeterol or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease. Ann Intern Med. 2007;146:545–555
- . Effects of tiotropium or combined therapy with salmeterol on hyperinflation in COPD. Osaka City Med J. 2007;53:25–34
- Concomitant treatment with nebulized formoterol and tiotropium in subjects with COPD: a placebo-controlled trial. Respir Med. 2008;102:479–487
- Superiority of “triple” therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD. Thorax. 2008;63:592–598
- Formoterol mono- and combination therapy with tiotropium in patients with COPD: a 6-month study. Respir Med. 2008;102:1511–1520
- Rational timing of combination therapy with tiotropium and formoterol in moderate and severe COPD. Respir Med. 2008;102:1701–1707
- Effects of arformoterol twice daily, tiotropium once daily, and their combination in patients with COPD. Respir Med. 2009;103:516–524
- . Formoterol and tiotropium compared with tiotropium alone for treatment of COPD. J COPD. 2009;6:17–25
- . Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1995;152:S77–S120
- . Lung volumes and forced ventilatory flow. Eur Respir J. 1993;6(Suppl. 16):5–40
- . Standardization of spirometry – 1994 update. Am J Respir Crit Care Med. 1995;152:1107–1136
- . The measurement of dyspnea: contents, interobserver agreement, and physiologic correlates of two new clinical indexes. Chest. 1984;85:751–758
- Long-term effects of a long-acting beta-2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N Engl J Med. 1992;328:1198–1203
- Long-acting bronchodilation with once-daily dosing of tiotropium (Spiriva) in stable chronic pulmonary disease. Am J Respir Crit Care Med. 2000;161:1136–1142
- . The MCID of the transition dyspnea index is a total score of one unit. J COPD. 2005;2:99–103
- A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma. N Engl J Med. 1992;327:1420–1425
- . Effect of tiotropium on circadian variation in airflow limitation in chronic obstructive pulmonary disease. Thorax. 2003;58:855–860
- . Tiotropium bromide, a new long-acting antimuscarinic bronchodilator: a pharmacodynamic study in patients with chronic obstructive pulmonary disease (COPD). Dutch Study Group. Eur Respir J. 1995;8:1506–1513
- . The effect of tiotropium, salmeterol and its combination on dynamic hyperinflation in COPD. Proc Am Thorac Soc. 2005;2:A542
- . Improved daytime spirometric efficacy of tiotropium compared with salmeterol in patients with COPD. Pulm Pharmacol Ther. 2005;18:397–404
- . Cross-talk between m3-Muscarinic and β2-adrenergic receptors at the level of receptor phosphorylation and desensitization. Mol Pharmacol. 1999;56:813–823
- . Muscarinic receptor – β-adrenoceptor cross-talk in airways smooth muscle. In: Zaagsma J, Meurs H, Roffel AF editor. Muscarinic Receptors in Airways Diseases. Basel, Boston, London: Birkhäuser Verlag; 2001;p. 121–157
- . Protein kinase C potentiates homologous desensitization of the β2-adrenoceptor in bovine tracheal smooth muscle. Eur J Pharmacol. 2006;529:151–156
☆ Study not registered in the Clinical Trials Registry; all patients were entered before implementation of the registry.
PII: S0954-6111(10)00087-9
doi: 10.1016/j.rmed.2010.02.017
© 2010 Elsevier Ltd. All rights reserved.
« Previous
Next »
Respiratory Medicine
Volume 104, Issue 7
, Pages 995-1004
, July 2010
