Respiratory Medicine
Volume 106, Issue 3 , Pages 329-337 , March 2012

Characterisation of asthma that develops during adolescence; findings from the Isle of Wight Birth Cohort

  • Ramesh J. Kurukulaaratchy

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • Respiratory Biomedical Research Unit, University of Southampton Faculty of Medicine, Southampton, SO16 6YD, United Kingdom
    • ,
  • Abid Raza

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • ,
  • Martha Scott

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • ,
  • Paula Williams

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • ,
  • Susan Ewart

      Affiliations

    • Large Animal Clinical Sciences, Michigan State University, East Lansing, Michigan, USA
    • ,
  • Sharon Matthews

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • ,
  • Graham Roberts

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • Respiratory Biomedical Research Unit, University of Southampton Faculty of Medicine, Southampton, SO16 6YD, United Kingdom
    • Human Development and Health, University of Southampton Faculty of Medicine, Southampton, SO16 6YD, United Kingdom
    • ,
  • S. Hasan Arshad

      Affiliations

    • The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom
    • Respiratory Biomedical Research Unit, University of Southampton Faculty of Medicine, Southampton, SO16 6YD, United Kingdom
    • Corresponding Author InformationCorresponding author. The David Hide Asthma & Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight PO30 5TG, United Kingdom. Tel.: +44 01983534373; fax: +44 01983822928.

Received 15 September 2011 ,Accepted 12 December 2011.

References 

  1. Sears MR, Greene JM, Willan AR, et al. A longitudinal, population-based, cohort study of childhood asthma followed to adulthood. N Engl J Med. 2003;349(15):1414–1422
  2. Phelan PD, Robertson CF, Olinsky A. The Melbourne asthma study: 1964–1999. J Allergy Clin Immunol. 2002;109:189–194
  3. Morgan WJ, Stern DA, Sherrill DL, et al. Outcomes of asthma and wheezing in the first 6 years of life. Follow-up through adolescence. Am J Respir Crit Care Med. 2005;172:1253–1258
  4. Haldar P, Pavord ID, Shaw DE, et al. Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med. 2008;178(3):218–224
  5. Stern DA, Morgan WJ, Halonen M, Wright AL, Martinez FD. Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort study. Lancet. 2008;372:1058–1064
  6. Mandhane PJ, Greene JM, Cowan JO, Taylor R, Sears MR. Sex differences in factors associated with childhood- and adolescent-onset wheeze. Am J Respir Crit Care Med. 2005;172:45–54
  7. Tollefsen E, Langhammer A, Romundstad P, Bjermer L, Johnsen R, Holmen TL. Female gender is associated with higher incidence and more stable respiratory symptoms during adolescence. Respiratory Med. 2007;101:896–902
  8. Nicolai T, Pereszlenyiova-Bliznakova L, Illi S, Reinhardt D, von Mutius E. Longitudinal follow-up of the changing gender ratio in asthma from childhood to adulthood: role of delayed manifestation in girls. Pediatr Allergy Immunol. 2003;14:280–283
  9. Rochat MK, Illi S, Ege MJ, et al. The Multicentre Allergy Study (MAS) Group Allergic rhinitis as a predictor for wheezing onset in school-aged children. J Allergy Clin Immunol. 2010;126:1170–1175
  10. Burgess JA, Walters EH, Byrnes GB, et al. Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study. J Allergy Clin Immunol. 2007;120:863–869
  11. Shaaban R, Zureik M, Soussan D, et al. Rhinitis and onset of asthma: a longitudinal population-based study. Lancet. 2008;372:1049–1057
  12. Kurukulaaratchy RJ, Arshad SH, Matthews S, Waterhouse LM. Factors influencing symptom expression in children with bronchial hyper-responsiveness at 10-years. J Allergy Clin Immunol. 2003;112(2):311–316
  13. Laprise C, Laviolette M, Boutet M, Boulet LP. Asymptomatic airway hyperresponsiveness: relationships with airway inflammation and remodelling. Eur Respir J. 1999;14:63–73
  14. for the SAPALDIA Team Brutsche MH, Downs SH, Schindler C. Bronchial hyperresponsiveness and the development of asthma and COPD in asymptomatic individuals: SAPALDIA cohort study. Thorax. 2006;61:671–677
  15. Genuneit J, Weinmayr G, Radon K, et al. Smoking and the incidence of asthma during adolescence: results of a large cohort study in Germany. Thorax. 2006;61:572–578
  16. Svanes C, Sunyer J, Plana E, Dharmage S, et al. Early life origins of chronic obstructive pulmonary disease. Thorax. 2010;65:14–20
  17. Beasley RW, Clayton TO, Crane J, et al. ISAAC Phase Three Study Group Acetaminophen use and risk of asthma, rhinoconjunctivitis and eczema in adolescents: International Study of Asthma and Allergies in Childhood: phase. Am J Respir Crit Care Med. 2011;183(2):171–178
  18. Arshad SH, Hide DW. Effect of environmental factors on the development of allergic disorders in infancy. J Allergy Clin Immunol. 1992 Aug;90(2):235–241
  19. Tariq SM, Matthews SM, Hakim EA, Stevens M, Arshad SH, Hide DW. The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study. J Allergy Clin Immunol. 1998;101:587–593
  20. Kurukulaaratchy RJ, Fenn M, Twiselton R, Matthews S, Arshad SH. The prevalence of asthma and wheezing illnesses amongst 10-year-old schoolchildren. Respir Med. 2002 Mar;96(3):163–169
  21. Asher MI, Keil U, Anderson HR, et al. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. Eur Respir J. 1995 Mar;8(3):483–491
  22. The EuroQol Group. EuroQol–a new facility for the measurement of health-related quality of life. Health Policy. 1990 Dec;16(3):199–208
  23. Scott M, Raza A, Karmaus W, et al. Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort. Thorax. 2010;65:258–262
  24. Paggiaro PL, Chanez P, Holz O, et al. Sputum induction. Eur Respir J Suppl. 2002 Sep;37:3s–8s
  25. Vink NM, Postma DS, Schouten JP, Rosmalen JGM, Boezen HM. Gender differences in asthma development and remission during transition through puberty: The TRacking Adolescents' Individual Lives Survey (TRAILS) study. J Allergy Clin Immunol. 2010;126:498–504
  26. Kurukulaaratchy RJ, Karmaus W, Raza A, Matthews S, Roberts G, Arshad SH. The influence of gender and atopy on the natural history of rhinitis in the first 18 years of life. Clin Exp Allergy. 2011; Jun;41(6):851–859
  27. Shaaban R, Zureik M, Soussan D, et al. Allergic rhinitis and onset of bronchial hyperresponsiveness. A population based study. Am J Respir Crit Care Med. 2007;176:659–666
  28. Demoly P, Bousquet J. The relationship between asthma and allergic rhinitis. Lancet. 2006;368(9357):711–713
  29. Rasmussen F, Taylor DR, Flannery EM, et al. Outcome in adulthood of asymptomatic airway hyperresponsiveness in childhood: a longitudinal population study. Pediatr Pulmonol. 2002;34:164–171
  30. Neve V, Girard F, Flahault A, Boule M. Lung and thorax development during adolescence: relationship with pubertal status. Eur Respir J. 2002;20:1292–1298
  31. Etminan M, Sadatsafavi M, Jafari S, Doyle-Waters M, Aminzadeh K, Fitzgerald JM. Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis. Chest. 2009;136:1316–1323
  32. Butland BK, Strachan DP. Asthma onset and relapse in adult life: the British 1958 birth cohort study. Ann Allergy Asthma Immunol. 2007;98:337–343
  33. Durham SR. In cooperation with the Global Allergy and Asthma European Network (GA2LEN) Passalacqua G, Durham SR. Allergic rhinitis and its impact on asthma update: allergen immunotherapy. J Allergy Clin Immunol. 2007;119:881–891

PII: S0954-6111(11)00472-0

doi: 10.1016/j.rmed.2011.12.006

Respiratory Medicine
Volume 106, Issue 3 , Pages 329-337 , March 2012

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