| Review Article |
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The effects of cigarette smoke on airway inflammation in asthma and COPD: Therapeutic implications
26 December 2011
Summary: Asthma and COPD are two chronic inflammatory disorders of the airway characterized by airflow limitation. While many similarities exist between these two diseases, they are pathologically dis...
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Asad Tamimi,
Dzelal Serdarevic,
Nicola A. Hanania
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319-328
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| Original Articles |
| Asthma and Allergy |
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Characterisation of asthma that develops during adolescence; findings from the Isle of Wight Birth Cohort
04 January 2012
Summary: Background: Understanding of adolescent-onset asthma remains limited. We sought to characterise this state and identify associated factors within a longitudinal birth cohort study. Methods: T...
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Ramesh J. Kurukulaaratchy,
Abid Raza,
Martha Scott,
Paula Williams,
Susan Ewart,
Sharon Matthews,
Graham Roberts,
S. Hasan Arshad
et al.
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329-337
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Adherence rate to beclomethasone dipropionate and the level of asthma control
22 December 2011
Summary: There are only a few studies assessing the relationship between adherence rate to ICS, as assessed by electronic monitoring, and the level of asthma control in childhood. The present study wa...
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Nulma S. Jentzsch,
Paulo Camargos,
Emanuel S.C. Sarinho,
Jean Bousquet
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338-343
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Status asthmaticus in the medical intensive care unit: A 30-year experience
22 December 2011
Summary: Objectives: To investigate the characteristics, trends in management (permissive hypercapnia; mechanical ventilation (MV); neuromuscular blockade) and their impact on complications and outcom...
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Jay I. Peters,
J. Eric Stupka,
Harjinder Singh,
Jill Rossrucker,
Luis F. Angel,
Jairo Melo,
Stephanie M. Levine
et al.
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344-348
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The role of SPINK5 in asthma related physiological events in the airway epithelium
02 December 2011
Summary: Background: Genetic studies have shown that variants in SPINK5 may be associated with atopic diseases and asthma. However, the functional role of SPINK5 protein in asthma has not been elucida...
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Esra Birben,
Cansın Sackesen,
Nihan Turgutoğlu,
Ömer Kalayci
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349-355
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| Bronchiectasis/Cystic Fibrosis |
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Pages |
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Outcomes of Pseudomonas eradication therapy in patients with non-cystic fibrosis bronchiectasis
28 December 2011
Summary: Pseudomonas aeruginosa infection is associated with poorer outcomes in non-cystic fibrosis bronchiectasis. It is unknown whether early eradication improves outcomes. This retrospective study ...
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Laura White,
Ghazi Mirrani,
Mark Grover,
Judith Rollason,
Adam Malin,
Jay Suntharalingam
et al.
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356-360
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| COPD |
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Author(s) |
Pages |
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The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway
30 November 2011
Summary: Patients with COPD are at risk for other comorbid diseases, like heart failure, coronary heart disease, and depression. However, little is known about COPD phenotypes and prevalence of sub-cl...
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Bjarte Gjerde,
Per S. Bakke,
Thor Ueland,
Jon A. Hardie,
Tomas M.L. Eagan
et al.
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361-366
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Impairment of quality of life in women with chronic obstructive pulmonary disease
24 October 2011
Summary: Background: There is ample evidence of the differences between genders in chronic obstructive pulmonary disease (COPD). The purpose of this study was to identify the factors that contribute t...
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Karlos Naberan,
Ángel Azpeitia,
Jordi Cantoni,
Marc Miravitlles
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367-373
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Barriers to adherence to COPD guidelines among primary care providers
14 October 2011
Summary: Background: Despite efforts to disseminate guidelines for managing chronic obstructive pulmonary disease (COPD), adherence to COPD guidelines remains suboptimal. Barriers to adhering to guide...
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Xavier Perez,
Juan P. Wisnivesky,
Linda Lurslurchachai,
Lawrence C. Kleinman,
Ian M. Kronish
et al.
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374-381
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Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: A randomized controlled study
05 October 2011
Summary: Background: The combination of tiotropium and fluticasone propionate/salmeterol (FSC) is commonly used to treat chronic obstructive pulmonary disease (COPD), but no study had evaluated the ef...
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Ki Suck Jung,
Hye Yun Park,
So Young Park,
Se Kyu Kim,
Young-Kyoon Kim,
Jae-Jeong Shim,
Hwa Sik Moon,
Kwan Ho Lee,
Jee-Hong Yoo,
Sang Do Lee
et al.
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382-389
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Development of the i-BODE: Validation of the incremental shuttle walking test within the BODE index
05 October 2011
Summary: Background: The BODE index has been shown to predict mortality in COPD. The index includes the 6 min walking test as the measure of exercise capacity. The incremental shuttle walking test (IS...
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Johanna E.A. Williams,
Ruth H. Green,
Vicki Warrington,
Michael C. Steiner,
Mike D.L. Morgan,
Sally J. Singh
et al.
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390-396
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Is chronic obstructive pulmonary disease associated with increased arterial stiffness?
05 December 2011
Summary: Objective: We hypothesize that airflow limitation is associated with increasing arterial stiffness and that having COPD increases a non-invasive measure of arterial stiffness – the aortic aug...
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Julie H. Janner,
David A. McAllister,
Nina S. Godtfredsen,
Eva Prescott,
Jørgen Vestbo
et al.
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397-405
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| Environmental & Occupational Lung Disease |
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Effect of cigarette smoking on cough reflex induced by TRPV1 and TRPA1 stimulations
30 December 2011
Summary: Background: Recent studies have shown that neurogenic inflammation induced by cigarette smoke is inhibited by TRPA1 antagonist, but not by TRPV1 antagonist. Since cough reflex sensitivity is ...
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Masashi Kanezaki,
Satoru Ebihara,
Peijun Gui,
Takae Ebihara,
Masahiro Kohzuki
et al.
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406-412
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The clinical implications of bronchoscopy in hemoptysis patients with no explainable lesions in computed tomography
14 December 2011
Summary: Introduction: Hemoptysis is observed frequently in patients, although chest computed tomography (CT) shows no explainable lesion as the cause of hemoptysis. However, the clinical course of th...
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Yeon Joo Lee,
Sang-Min Lee,
Jong Sun Park,
Jae-Joon Yim,
Seok-Chul Yang,
Young Whan Kim,
Sung Koo Han,
Jae Ho Lee,
Choon-Taek Lee,
Ho Il Yoon,
Chul-Gyu Yoo
et al.
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413-419
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| Interstitial Lung Disease |
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Sleep desaturation and its relationship to lung function, exercise and quality of life in LAM
05 January 2012
Summary: Background: Lymphangioleiomyomatosis (LAM) is characterised by progressive airway obstruction and hypoxaemia in young women. Although sleep may trigger hypoxaemia in patients with airway obst...
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Pedro Medeiros,
Geraldo Lorenzi-Filho,
Suzana P. Pimenta,
Ronaldo A. Kairalla,
Carlos R.R. Carvalho
et al.
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420-428
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Predictors of benefit following pulmonary rehabilitation for interstitial lung disease
19 December 2011
Summary: Background: Pulmonary rehabilitation improves functional capacity and symptoms in the interstitial lung diseases (ILDs), however there is marked variation in outcomes between individuals. The...
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Anne E. Holland,
Catherine J. Hill,
Ian Glaspole,
Nicole Goh,
Christine F. McDonald
et al.
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429-435
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Acute exacerbation of IPF following diagnostic bronchoalveolar lavage procedures
05 December 2011
Summary: Backgrounds: Bronchoalveolar lavage (BAL) is generally regarded as a safe diagnostic procedure. However, acute exacerbation after BAL is increasingly recognized as a specific complication for...
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Koji Sakamoto,
Hiroyuki Taniguchi,
Yasuhiro Kondoh,
Kenji Wakai,
Tomoki Kimura,
Kensuke Kataoka,
Naozumi Hashimoto,
Osamu Nishiyama,
Yoshinori Hasegawa
et al.
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436-442
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| Lung Cancer and Oncologic Disorders |
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Adverse pulmonary reactions associated with the use of monoclonal antibodies in cancer patients
12 December 2011
Summary: Background: The incidence and clinical characteristics of adverse pulmonary reactions resulting from anticancer monoclonal antibody (mAbs) therapy have not been well described. We determined ...
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Hyo Jae Kang,
Jong Sun Park,
Dong-Wan Kim,
Jinwoo Lee,
Yun Jeong Jeong,
Sun Mi Choi,
Sang-Min Lee,
Seok-Chul Yang,
Chul-Gyu Yoo,
Young Whan Kim,
Sung Koo Han,
Jae-Joon Yim
et al.
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443-450
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| Pulmonary Infections |
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Guideline adherence and macrolides reduced mortality in outpatients with pneumonia
19 December 2011
Summary: Background: For outpatients with pneumonia, guidelines recommend empiric antibiotics and some suggest macrolides are preferred agents. We hypothesized that both guideline-concordant antibioti...
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Leyla Asadi,
Dean T. Eurich,
John-Michael Gamble,
Jasjeet K. Minhas-Sandhu,
Thomas J. Marrie,
Sumit R. Majumdar
et al.
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451-458
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| Sleep |
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Nocturnal gastroesophageal reflux, lung function and symptoms of obstructive sleep apnea: Results from an epidemiological survey
26 December 2011
Summary: Background: Nocturnal gastroesophageal reflux (nGER) has received increasing interest as a predisposing factor for respiratory diseases and sleep disturbances. The possible role of obstructiv...
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Össur Ingi Emilsson,
Christer Janson,
Bryndís Benediktsdóttir,
Sigurdur Júlíusson,
Thórarinn Gíslason
et al.
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459-466
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| Short Communication |
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Chronic bronchitis in the general population: Influence of age, gender and socio-economic conditions
26 December 2011
Summary: Chronic bronchitis (CB) is an indicator of an increased risk of developing COPD, but its symptoms are often underestimated. Demographic and socio-economic conditions might influence its preva...
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Alexis Ferré,
Claire Fuhrman,
Mahmoud Zureik,
Christos Chouaid,
Alain Vergnenègre,
Gérard Huchon,
Marie-Christine Delmas,
Nicolas Roche
et al.
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467-471
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