Original article| Volume 45, ISSUE 4, P165-171, October 1951

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Friedländer pneumonia

A report of eight cases treated by chemo-therapy
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      • 1.
        Eight cases of Friedländer pneumonia are described, 6 of which recovered.
      • 2.
        These 8 cases were all seen within a period of thirteen months (December 31, 1948, to January 31, 1950).
      • 3.
        Five of the 6 survivors were cured by streptomycin after penicillin treatment had failed.
      • 4.
        One patient, in whom the pneumo-bacillus was partially sensitive to penicillin, was cured by penicillin alone.
      • 5.
        The 2 patients who died both did so suddenly and unexpectedly, after several days of well-being and normal temperature had succeeded an apparent response to streptomycin.
      • 6.
        In 1 of the fatal cases a lung abscess was found at autopsy, in the right upper lobe; and in the other, an abscess in the right lower lobe was suspected clinically. No other lung abscess was diagnosed, clinically or radiologically.
      • 7.
        Of the 8 cases, the disease was confined to the lower lobes in 6, although multilobar infection occurred in 5.
      • 8.
        The leucocyte count was high in 4 cases, but in 2 of these evidence of suppuration was present.
      • 9.
        It is suggested that the sulphonamide treatment given by the home doctor may have slowed, or temporarily checked, the progress of the disease, thus accounting for the fact that 3 of the 8 patients were less seriously ill than those described in the literature.
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