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Abstract
Dry powder inhalers are designed with resistance to airflow so that a respirable cloud of particles is generated during inhalation. Some of these devices require a certain inhalation rate to produce a consistent dose of respirable particles. The aim of the study was to determine the inhalation rate of elderly patients with chronic obstructive pulmonary disease (COPD) when they inhale through a Turbuhaler®and assess the potential of the In-Check Meter®to identify inhalation rates. Their peak inhalation rate using a normal inhalation, pre- and post-counselling, was measured using a Turbuhaler Trainer®and an In-Check Meter®. Spirometry was also measured. Seventy-four COPD patients with a mean (![Math Eq]()
) age of 79·7 (8·4) years and forced expiratory volume in 1 sec (FEV1) 41·9 (12·8)% predicted. Pre-counselling 14 obtained a rate of <30 l min−1with the Turbuhaler Trainer, 31 from 30 to 40 min−1, 23 between 40–60 l min−1and 6 >60 l min−1. The median (range) peak inhalation rates with the In-Check Meter®were 50 (50–70), 70 (50–130), 100 (60–200) and 225 (200–250) l min−1. Post-counselling 7, 16, 41 and 10 achieved the respective peak inhalation rates using the Turbuhaler Trainer®Similarly, the In-Check inhalation rates were 50 (50–60), 70 (50–130), 90 (60–200) and 250 (200–270) l min−1. The results highlight the potential of the In-Check Meter®to identify patients' inhalation rates through dry powder inhalers.
) age of 79·7 (8·4) years and forced expiratory volume in 1 sec (FEV1) 41·9 (12·8)% predicted. Pre-counselling 14 obtained a rate of <30 l min−1with the Turbuhaler Trainer, 31 from 30 to 40 min−1, 23 between 40–60 l min−1and 6 >60 l min−1. The median (range) peak inhalation rates with the In-Check Meter®were 50 (50–70), 70 (50–130), 100 (60–200) and 225 (200–250) l min−1. Post-counselling 7, 16, 41 and 10 achieved the respective peak inhalation rates using the Turbuhaler Trainer®Similarly, the In-Check inhalation rates were 50 (50–60), 70 (50–130), 90 (60–200) and 250 (200–270) l min−1. The results highlight the potential of the In-Check Meter®to identify patients' inhalation rates through dry powder inhalers.Keywords
References
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Article info
Publication history
Accepted:
August 6,
2001
Received:
February 7,
2001
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© 2001 Harcourt Publishers Ltd. Published by Elsevier Inc.
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