Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19)

  • Giuseppe Lippi
    Affiliations
    Section of Clinical Biochemistry, Department of Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy
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  • Brandon Michael Henry
    Correspondence
    Corresponding author. Cardiac Intensive Care Unit, The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
    Affiliations
    Cardiac Intensive Care Unit, The Heart Institute, Cincinnati Children's Hospital Medical Center, Ohio, USA
    Search for articles by this author
Published:March 24, 2020DOI:https://doi.org/10.1016/j.rmed.2020.105941
      Coronavirus disease 2019 (COVID-19) is a respiratory and systemic illness that may progress to severe hypoxemia needing some form of ventilatory support in as many as 15–20% of suspected and confirmed cases [
      • Qiu H.
      • Tong Z.
      • Ma P.
      • Hu M.
      • Peng Z.
      • Wu W.
      • Du B.
      China critical care clinical trials group (CCCCTG). Intensive care during the coronavirus epidemic.
      ]. In outbreak regions, the surge in critically ill patients has placed significant strain on intensive care units (ICUs), with volume demands that overwhelm current capacity [
      • Qiu H.
      • Tong Z.
      • Ma P.
      • Hu M.
      • Peng Z.
      • Wu W.
      • Du B.
      China critical care clinical trials group (CCCCTG). Intensive care during the coronavirus epidemic.
      ]. There is a compelling need to identify clinical predictors of severe COVID-19 to enable risk stratification and optimize resource allocation.

      Keywords

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