Highlights
- •Using inhaler devices correctly is critical for chronic lung disease management.
- •Poor inhaler technique continues to be a recurring theme in asthma and COPD.
- •A dedicated service can focus on teaching patients to use inhalers correctly.
- •Improving the use of inhalers prevents future exacerbations and hospital admissions.
- •Patients value the use of a dedicated service to teach correct inhaler use.
Abstract
Background
The management of asthma and COPD is largely dependent on patients being able to use
their inhaled medication correctly, but poor inhaler technique continues to be a recurring
theme in studies and clinical practice. This is associated with poor disease control,
increased risk of exacerbations and hospital admissions, and so there is a need to
redesign services for patients to optimise their medicines use.
Methods
A novel ward-based dedicated inhaler technique service was developed, and pharmacy
support workers trained to provide this, focusing on optimising inhaler technique
using a checklist and recommending protocol-guided inhaler device switches. Inpatients
on adult respiratory wards with a diagnosis of exacerbation of asthma or COPD consented
to receive this service, and the impact on exacerbations and hospital admissions were
compared in the 6-months before and after the intervention.
Results
266 adults (74 asthma, 188 COPD, and four asthma-COPD overlap) received the inhaler
technique service. Six-month exacerbation and hospital admission data were available
for 184 subjects. Optimising inhaler technique achieved a significant reduction in
the combined asthma and COPD annualised rate of moderate-to-severe exacerbations (Rate
Ratio [RR] 0.75, p < 0.05) and annualised rate of hospital admissions (RR 0.57, p < 0.0005).
Improvements were also observed in future length of stay (- 1.6 days) and the average
cost of admission (-£748).
Conclusions
This novel inhaler technique service produced a significant reduction in the rate
of moderate-to-severe exacerbations of asthma and COPD, and a reduction in the rate
hospital admissions, length of stay and average cost of admission.
Keywords
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References
- Comparison of gamma scintigraphy and a pharmacokinetic technique for assessing pulmonary deposition of terbutaline sulphate delivered by pressurized metered dose inhaler.Pharmaceut. Res. 1995; 12: 231-236https://doi.org/10.1023/a:1016278926231
- Aerosol deposition considerations in inhalation therapy.Chest. 1985; 88: 152S-160Shttps://doi.org/10.1378/chest.88.2_supplement.152s
- In vitro comparison of three salbutamol containing multidose dry powder inhalers: buventol Easyhaler(R), Inspiryl Turbuhaler(R) and Ventoline Diskus(R).Clin. Drug Invest. 2000; 20: 25-33https://doi.org/10.2165/00044011-200020010-00004
- Inhaler mishandling remains common in real life and is associated with reduced disease control.Respir. Med. 2011; 105: 930-938https://doi.org/10.1016/j.rmed.2011.01.005
- Systematic review of errors in inhaler use: has patient technique improved over time?.Chest. 2016; 150: 394-406https://doi.org/10.1016/j.chest.2016.03.041
- Asthma control: importance of compliance and inhaler technique assessments.J. Asthma. 2014; 51: 429-434https://doi.org/10.3109/02770903.2013.871558
- Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability.Eur. Respir. J. 2002; 19: 246-251https://doi.org/10.1183/09031936.02.00218402
- Inhaler technique and asthma: feasability and acceptability of training by pharmacists.Respir. Med. 2011; 105: 1815-1822https://doi.org/10.1016/j.rmed.2011.07.004
- Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes.Respir. Res. 2018; 19: 10https://doi.org/10.1186/s12931-017-0710-y
- Checklists for powder inhaler technique: a review and recommendations.Respir. Care. 2014; 59: 1140-1154https://doi.org/10.4187/respcare.02342
- Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care.J. Aerosol Med. 2003; 16: 249-254https://doi.org/10.1089/089426803769017613
- The Battle for Breath – the Impact of Lung Disease in the UK.2016 (Available at:)
- Association between COPD exacerbations and lung function decline during maintenance therapy.Thorax. 2020; 75: 744-753https://doi.org/10.1136/thoraxjnl-2019-214457
- Why asthma still kills.(Available at:)
- Evaluation of a novel educational strategy, including inhaler-based reminder labels, to improve asthma inhaler technique.Patient Educ. Counsel. 2008; 72: 26-33https://doi.org/10.1016/j.pec.2008.01.014
- Global strategy for asthma management and prevention.(Available from:)www.ginasthma.orgDate: 2020
- Global strategy for prevention, diagnosis and management of COPD.(Available from:)www.goldcopd.orgDate: 2021
- National Asthma and Chronic Obstructive Pulmonary Disease Audit Programme (NACAP): Adult Asthma Clinical Audit 2019/20 (Adults with Asthma Attacks Discharged from Hospitals in England, Scotland and Wales between 1 April 2019 and 31 March 2020). Clinical Audit Report.RCP, London2021
- National Asthma and Chronic Obstructive Pulmonary Disease Audit Programme (NACAP). COPD Clinical Audit 2019/20 (People with COPD Exacerbations Discharged from Acute Hospitals in England, Scotland and Wales between October 2019 and February 2020). Data Analysis and Methodology Report.RCP, LondonJune 2021
- Prescription Cost Analysis, England –.2019 (Publication date: 16th April 2020. Available at:) (Accessed 17th November 2020)
- Do healthcare professionals have sufficient knowledge of inhaler techniques in order to educate their patients effectively in their use?.Thorax. 2010; 65: A117-A118https://doi.org/10.1136/thx.2010.150979.45
- Inadequate skill of healthcare professionals in using asthma inhalation devices.J. Asthma. 2007; 44: 593-598https://doi.org/10.1080/02770900701554334
- Inhaler education for hospital-based pharmacists: how much is required?.Can. Respir. J. J. Can. Thorac. Soc. 1999; 6: 237-244https://doi.org/10.1155/1999/695365
- Long-term maintenance of pharmacists' inhaler technique demonstration skills.Am. J. Pharmaceut. Educ. 2009; 73: 32https://doi.org/10.5688/aj730232
- The ability of the community pharmacist to learn the proper actuation techniques of inhaler devices.J. Allergy Clin. Immunol. 2001 Dec; 108: 918-920https://doi.org/10.1067/mai.2001.119153
- Inhaler technique mastery and maintenance in healthcare professionals trained on different devices.J. Asthma. 2018; 55: 79-88https://doi.org/10.1080/02770903.2017.1310227
- A global picture of pharmacy technician and other pharmacy support workforce cadres.Res. Soc. Adm. Pharm. 2017; 13: 271-279https://doi.org/10.1016/j.sapharm.2016.12.004
- Inhaler standards and competency document.(Available at:)
- Inhaler errors in the CRITIKAL study: type, frequency, and association with asthma outcomes.J Allergy Clin Immunol Pract. 2017; 5: 1071-1081https://doi.org/10.1016/j.jaip.2017.01.004
- Inhaler competence in asthma: common errors, barriers to use and recommended solutions.Respir. Med. 2013; 107: 37-46https://doi.org/10.1016/j.rmed.2012.09.017
- Inhaler technique maintenance: gaining an understanding from the patient's perspective.J. Asthma. 2011; 48: 616-624https://doi.org/10.3109/02770903.2011.580032
- Metered-dose inhalers: do health care providers know what to teach?.Arch. Intern. Med. 1993; 153: 81-85https://doi.org/10.1001/archinte.153.1.81
- Metered-dose inhalers: do emergency health care providers know what to teach?.Ann. Emerg. Med. 1995; 26: 308-311https://doi.org/10.1016/s0196-0644(95)70078-1
- Physicians' metered dose inhaler technique after a single teaching session.Ann. Allergy Asthma Immunol. 1996; 76: 145-148https://doi.org/10.1016/S1081-1206(10)63413-8
- Comparison of small-group training with self-directed internet-based training in inhaler techniques.Am. J. Pharmaceut. Educ. 2009; 73: 85https://doi.org/10.5688/aj730585
- Effect of pharmacist-led interventions on medication adherence and inhalation technique in adult patients with asthma or COPD: a systematic review and meta-analysis.J. Clin. Pharm. Therapeut. 2020; 45: 904-917https://doi.org/10.1111/jcpt.13126
- Effectiveness of pharmaceutical care for patients with chronic obstructive pulmonary disease (PHARMACOP): a randomized controlled trial.Br. J. Clin. Pharmacol. 2013; 77: 756-766https://doi.org/10.1111/bcp.12242
Article info
Publication history
Published online: August 23, 2021
Accepted:
August 20,
2021
Received in revised form:
June 25,
2021
Received:
April 7,
2021
Identification
Copyright
Crown Copyright © 2021 Published by Elsevier Ltd. All rights reserved.