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    • Research Article
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      Effects of nutritional supplementation combined with low-intensity exercise in malnourished patients with COPD

      Respiratory Medicine
      Vol. 104Issue 12p1883–1889Published online: June 7, 2010
      • Keiyu Sugawara
      • Hitomi Takahashi
      • Chikage Kasai
      • Noritaka Kiyokawa
      • Tohru Watanabe
      • Sayaka Fujii
      • and others
      Cited in Scopus: 84
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        The first aim of this study was to investigate the effects of nutritional supplementation combined with low-intensity exercise on body components, exercise tolerance, and health-related quality of life (HRQOL) in malnourished patients with COPD. The second aim of this study was to examine the degree of systemic inflammation and the actual changes in levels of systemic CRP, TNFα, IL-6 and IL-8 actual changes after a combination of nutritional supplementation and low-intensity exercise in these patients.
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